manti

We have hosted the application manti in order to run this application in our online workstations with Wine or directly.

Quick description about manti:

MANTI is a one-stop shop N-termini annotation & evaluation solution. MANTI was previously (un)known as muda.pl ahead of v3.7, the project was renamed to MANTI.pl with v3.7 on 2019-06-24.

It congregates information from 4 (or optionally 5) different MaxQuant output files into a master file suitable explicitly for protein neo-termini analyses. The central anchor for the data congregation is the modificationSpecificPeptides.txt file - additional data is inferred from different other source files from the MaxQuant txt folder. Maybe also useful for normal proteomics purposes but this script is heavily optimized for protein neo-termini identification and validation. A graphical interface is available as Yo?urtlu_MANTI (a Perl/Tk script) + execut. application versions for Win10 without the need to have Perl installed locally.
For a very detailed explanation of script parameters and the evaluation strategy, please consult the extensive manual PDF files accompanying each release.

Features:

• MaxQuant N-termini evaluation
• Protein-Termini evaluation & validation
• (UniProt) data annotation & assembly
• Limma, LOCALIZER, TargetP2.0 & TopFINDer integration
• Re-mapping of identified Termini to correct Isoforms
• Plenty of visualization options with supplied R scripts

Audience: Science/Research.
User interface: Command-line.
Programming Language: Perl.
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