hierachical dnacoder to run in linux online online with Winfy
We have hosted the application hierachical dnacoder to run in linux online in order to run this application in our online workstations with Wine or directly.
Quick description about hierachical dnacoder to run in linux online:
The storage and data transferring of large genome data are becoming important concerns for biomedical researchers. We present a novel multi-reference based genome compression method with a hierachical structure. Our approach works for the de facto standard alignment format (i.e., BAM) compression that is the pressing need at present. We align new sequences to a reference sequence using SOAP3, a GPU-based aligning software, and summarize mapping properties and information for exact mapped reads. To increase the exact aligning rate, we also realign the approximately mapped and unmapped reads by changing the reference sequence or shortening the read length. Meanwhile, we further the study using �lossy� quality values through k-means clustering scheme and find its minute effect on downstream applications. The proposed method has achieved compression ratios from 0.5 to 0.65, which corresponds to space savings of 35%-50%, on experimental datasets.Features:
- Efficient
- Fast
- Promising
Audience: Information Technology, Science/Research, Engineering.
Programming Language: C++.
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