allelome pro online with Winfy

We have hosted the application allelome pro in order to run this application in our online workstations with Wine or directly.


Quick description about allelome pro:

Detecting allelic biases from high-throughput sequencing data requires an approach that maximises
sensitivity while minimizing false positives. Here we present Allelome.PRO, an automated userfriendly
bioinformatics pipeline, which uses high-throughput sequencing data from reciprocal crosses
of two genetically distinct mouse strains to detect allele-specific expression and chromatin
modifications. Allelome.PRO extends approaches used in previous studies that exclusively analysed
imprinted expression to give a complete picture of the �allelome� by automatically categorising the
allelic expression of all genes in a given cell type into imprinted, strain-biased biallelic or noninformative.
Allelome.PRO offers increased sensitivity to analyse lowly expressed transcripts, together
with a robust false discovery rate empirically calculated from variation in the sequencing data.

Audience: Science/Research.
User interface: Command-line.
Programming Language: Unix Shell, Perl, S/R.

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